Ocular manifestations of sickle cell disease in heterozygous subjects: Senegalese experience

Sickle cell disease is a genetic disease with autosomal recessive transmission due to the presence in the red blood cell of abnormal hemoglobin called hemoglobin S. It would be the most widespread hemoglobinopathy in the world affecting nearly 120 million people according to the WHO. This disease is very frequent in Africa south of Sahara, where in Senegal it affects almost 10% of the population. It is responsible for polymorphic clinical manifestations, in particular ophthalmologic. However, the latter are very little described by the literature in our country. We report our experience of ocular lesions found in heterozygous sickle cell subjects monitored in our department.