Wenrui Zhao, Suyao Li, Ruoxue Chen, J. Ni, Xuan Huang, Song Li, Xiaoling Lu, Xin Cao
{"title":"RXR信号靶向癌症治疗","authors":"Wenrui Zhao, Suyao Li, Ruoxue Chen, J. Ni, Xuan Huang, Song Li, Xiaoling Lu, Xin Cao","doi":"10.59717/j.xinn-life.2023.100014","DOIUrl":null,"url":null,"abstract":") and truncated RXRα (tRXRα). Meanwhile, RXR-modulating drugs began to attract more interest from oncologists because of their potential in interfering with cancer cell proliferation, differentiation, and apoptosis according to the important and comprehensive regulation effects of RXR in tumorigenesis. Herein, we will review the comprehensive role of RXR between RXR signaling and oncogenesis, with a highlighted focus on the undervalued rexinoid-related cancer therapy, and discuss and propose its great potential in future clinics.","PeriodicalId":189912,"journal":{"name":"The Innovation Life","volume":"10 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"RXR signaling targeted cancer therapy\",\"authors\":\"Wenrui Zhao, Suyao Li, Ruoxue Chen, J. Ni, Xuan Huang, Song Li, Xiaoling Lu, Xin Cao\",\"doi\":\"10.59717/j.xinn-life.2023.100014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\") and truncated RXRα (tRXRα). Meanwhile, RXR-modulating drugs began to attract more interest from oncologists because of their potential in interfering with cancer cell proliferation, differentiation, and apoptosis according to the important and comprehensive regulation effects of RXR in tumorigenesis. Herein, we will review the comprehensive role of RXR between RXR signaling and oncogenesis, with a highlighted focus on the undervalued rexinoid-related cancer therapy, and discuss and propose its great potential in future clinics.\",\"PeriodicalId\":189912,\"journal\":{\"name\":\"The Innovation Life\",\"volume\":\"10 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The Innovation Life\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.59717/j.xinn-life.2023.100014\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Innovation Life","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.59717/j.xinn-life.2023.100014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
) and truncated RXRα (tRXRα). Meanwhile, RXR-modulating drugs began to attract more interest from oncologists because of their potential in interfering with cancer cell proliferation, differentiation, and apoptosis according to the important and comprehensive regulation effects of RXR in tumorigenesis. Herein, we will review the comprehensive role of RXR between RXR signaling and oncogenesis, with a highlighted focus on the undervalued rexinoid-related cancer therapy, and discuss and propose its great potential in future clinics.
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