结缔组织发育不良青少年脑静脉血流动力学受损的症状

A. Proshin, V. Mashin, L. Belova, D. Belov
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引用次数: 0

摘要

本文旨在探讨结缔组织发育不良(CTD)青少年脑静脉功能不全的临床表现。材料与方法。作者调查了156名青少年。主要组为82名有CTD症状的青少年。对照组为74例无CTD表现的青少年。根据L.N. Abakumova评分系统(2006)评估结缔组织发育不良。患者的摄入和检查显示脑静脉功能不全的临床症状。结果。主组患者特有的主诉有:头痛,在倾斜体位工作时、夜间睡眠期间或之后,头痛强度增加,伴有咳嗽和紧张,在下午和适度体育活动后减轻;眩晕,在姿势改变、头部旋转和弯曲的情况下加重;早晨脸、眼皮浮肿/苍白,“高枕”症状,“紧领”症状,早晨有沙砾感;做恶梦,因头痛而频繁夜间醒来;鼻塞,无ARD症状。主组患者还表现出脑静脉功能不全的症状:面部浮肿、眼睑肿胀;巩膜注射;前胸/颈部静脉网;唇或鼻唇三角紫绀,三叉神经第一或第二支感觉减退。结论。青少年CTD患者脑静脉功能不全的临床症状较对照组更为突出。这一事实表明,需要早期发现静脉血流动力学障碍,随后进行动态监测和预防措施,以避免青少年脑血管疾病的早期发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
SYMPTOMS OF IMPAIRED CEREBRAL VENOUS HEMODYNAMICS IN ADOLESCENTS WITH CONNECTIVE TISSUE DYSPLASIA
The aim of the paper was to study clinical manifestations of cerebral venous insufficiency in adolescents with connective tissue dysplasia (CTD). Materials and Methods. The authors examined 156 adolescents. The main group consisted of 82 adoles-cents with CTD symptoms. The comparison group included 74 adolescents without CTD manifestations. Connective tissue dysplasia was assessed according to L.N. Abakumova scoring system (2006). Patient intake and examination revealed clinical signs of cerebral venous insufficiency. Results. The following complaints were peculiar for the patients of the main group: headache, which in-tensity increased when working in an inclined position, during or after a nocturnal sleep, with coughing and on straining, and decreased in the afternoon and after moderate physical activity; vertigo, which worsened in case of postural change, head rotation and bending; puffiness/pasty face and eyelids in the morning, “high pillow” symptom, “tight collar” symptom, sandy-gritty sensation in the morning; night-mares, frequent night awakenings because of the headaches; nasal stuffiness without ARD symptoms. The patients of the main group also demonstrated symptoms of cerebral venous insufficiency: facial puffi-ness, eyelid swelling; sclera injection; venous network on the anterior chest / neck; lip or nasolabial tri-angle cyanosis, hypoesthesia of the 1st or 2nd branch of the trigeminal nerve. Conclusion. Clinical symptoms of cerebral venous insufficiency are more prominent in adolescents with CTD than in the comparison group. This fact indicates the need for early detection of venous hemodynam-ic disorders, subsequent dynamic monitoring and preventive measures to avoid the early development of cerebrovascular diseases in adolescents.
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