不同年龄组多发病儿童慢性扁桃体炎的临床及形态学特征

N. M. Khmel’nitskaya, E. Bezrukova, R. C. Makhmudov, L. Mkrtchyan
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摘要

本研究的目的是确定不同年龄段多发病儿童肥大和慢性扁桃体炎的主要临床、形态学和免疫组织化学表现。材料和方法。研究对象为48例儿童扁桃体切除术(含6岁以下)和扁桃体切除术(含7岁以上)后的病史和手术资料。确定了4个年龄组的儿童。定性评价腭扁桃体上皮细胞、结缔组织上皮下层、腔隙、滤泡及滤泡间淋巴组织含量、间质成分以及T淋巴细胞和b淋巴细胞在腭扁桃体组织中的分布。6岁以下儿童患者的腭扁桃体淋巴组织的形态学变化表明,在与大多数外来入侵者的相互作用中,免疫活性保持不变。在13 - 18岁的儿童中,由于纤维化导致的淋巴组织体积减少最为明显。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical and morphological features of chronic tonsillitis of frequently ill children of different age groups
The aim of the research is to determine the main clinical, morphological and immunohistochemical manifestations of hypertrophy and chronic tonsillitis in different age groups of children who are frequently ill. Materials and methods. The objects of the research were the medical histories and surgical materials after tonsillotomy (patients under the age of 6 inclusive) and tonsillectomy (patients from 7 years old) of 48 children’s tonsils. 4 age groups of children were identified. Qualitative assessment of epithelial cells, subepithelial layer of connective tissue, contents of lacunae, follicular and interfollicular lymphoid tissue, stromal component of palatine tonsils as well as distribution of T- and B-lymphocytes in palatine tonsils’ tissue was performed. Morphological changes in the lymphoid tissue of palatine tonsils in children of patients under the age of 6 indicate the preservation of immune activity during interaction with most foreign invader. The most pronounced decrease in the volume of lymphoid tissue because of fibrosis is observed in children between the ages 13 – 18 years old.
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