Research progress of endometrial microecology in infertile women

: There are many causes of infertility, some of which are unknown, which bring difficulties to the diagnosis and treatment of infertility.With the further deepening of human understanding of microecology and the development of 16s rRNA gene sequencing and other technologies, it is gradually recognized that the endometrium is not a sterile environment, and there is a correlation between microecological imbalance and infertility. The endometrial microbiome may have a previously unrecognized role in uterine physiology and human reproduction. The analysis of endometrial microbiota is helpful to find the risk factors of reproductive tract diseases and provide guidance and help for the treatment of infertility. This article mainly reviews the research progress of female endometrial microecology in recent years, in order to improve the treatment methods and clinical outcomes of infertility.