母乳喂养和感染艾滋病毒的妇女:是否有可能超越这种回避?

Carlea Annunziata, Mazzarelli Laura Letizia, Sarno Laura, Fulgione Caterina, Mantelli Dalila, G. Maurizio
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引用次数: 0

摘要

在没有母体抗逆转录病毒治疗和婴儿抗逆转录病毒预防的情况下,母乳喂养期间母婴传播艾滋病毒1的风险为10%至15%。世卫组织2016年指南建议,感染艾滋病毒并完全支持坚持抗逆转录病毒治疗的妇女应母乳喂养至少12个月至24个月或更长时间。无论如何,在高收入环境中,建议感染艾滋病毒的妇女避免母乳喂养,无论母亲的病毒载量或抗逆转录病毒治疗状况如何。母乳喂养在低收入和中等收入环境中的优势已得到充分认识。这篇简短的叙述性综述旨在总结关于母乳喂养期间艾滋病毒传播的机制和危险因素的现有证据,以及在抗逆转录病毒治疗坚持的背景下可能的预防策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Breastfeeding and women living with HIV: Is it possible to move beyond the avoidance?
The risk of mother-to-infant transmission of HIV 1 during breastfeeding ranges from 10% to 15% in the absence of maternal Antiretroviral Therapy (ART) and infant Antiretroviral (ARV) prophylaxis. WHO guidelines 2016 recommend women living with HIV and fully supported for ART adherence should breastfeed for at least 12 months and up to 24 months or longer. Anyway, in high-income settings, women living with HIV are suggested to avoid breastfeeding, regardless of maternal viral load or antiretroviral therapy status. The advantages of breastfeeding in low and middle-income settings are well recognized. This brief narrative review aims to summarize existing evidence on mechanisms and risk factors for HIV transmission during breastfeeding and the possible prevention strategies in the context of ART adherence.
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