肝移植受者结核:一项系统综述

Devita Nur Amelia
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引用次数: 0

摘要

背景:尽管声称,移植受者的结核病发病率是随机的。移植后结核的发生率取决于移植器官、移植前潜伏结核筛查和既往抗结核药物。这一比率还可能取决于接受者和供体结核病的发病率。与普通人群相比,实体器官移植后的活动性肺结核使移植物丢失和死亡的风险增加了4倍。目的:探讨肝移植受者与结核杆菌的关系。方法:本研究显示,通过查看系统评价和荟萃分析(PRISMA) 2020指南的首选报告项目,它满足了所有要求。因此,专家们可以确保这项研究尽可能是最新的。搜索方法使用了许多电子参考数据库,如Pubmed和SagePub,来查找2000年至2023年之间发表的论文。我们没有看评论论文,已经发表的文章,或者只做了一半的文章。结果:在PubMed数据库中,我们搜索的结果是66篇文章,而在SagePub上搜索的结果是23篇文章。2013年最后一年的搜索结果显示,PubMed总共有23篇文章,SagePub有18篇文章。最后,我们一共编辑了20篇论文,其中16篇来自PubMed, 4篇来自SagePub。我们纳入了5项符合标准的研究。结论:器官移植患者发生潜伏性结核的危险性较高。这表明在肝移植后患者中使用预防性药物如异烟肼的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TUBERCULOSIS IN LIVER TRANSPLANT RECIPIENT : A SYSTEMATIC REVIEW
Background: Despite claims, transplant recipients' TB rates are random. The rate of posttransplant tuberculosis depends on the organ transplanted, pre-transplant latent tuberculosis screening, and previous antituberculosis medication. This rate may also depend on recipient and donor tuberculosis rates. Active tuberculosis after solid organ transplantation increases the risk of graft loss and death four-fold compared to the general population. Aim: This article examines the link between tubercolis and liver transplant recipient. Methods: This study showed that it met all of the requirements by looking at the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020 guidelines. So, the experts could make sure that the study was as current as possible. The search method used a number of electronic reference databases, such as Pubmed and SagePub, to look for papers that were published between 2000 and 2023. We didn't look at review papers, articles that had already been published, or articles that were only half done. Result: In the PubMed database, the results of our search brought up 66  articles, whereas the results of our search on SagePub brought up 23 articles. The results of the search conducted for the last year of 2013 yielded a total of 23 articles for PubMed and 18 articles for SagePub. In the end, we compiled a total of 20 papers, 16 of which came from PubMed and four of which came from SagePub. We included five research that met the criteria. Conclusion: Patients who have undergone organ transplantation are at high risk of developing latent TB. This shows the importance of administering prophylactic drugs such as isoniazid in post-liver transplant patients.
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