Features of the blood coagulation system status in patients with uterine fibroids: a literature review

Currently, uterine fibroids are one of the most common gynecological diseases, with surgical treatments provided in many cases, but hormone therapy is widely used. Gynecologists must consider all aspects of the patients condition during treatment, including the blood coagulation system status. Features of hemostasis affect the disease development, features and outcomes of the operation, and the postoperative period course, as well as the possibility of carrying out the necessary drug therapy and its results. This literature review reflects the results of research by domestic and foreign authors regarding the hemostasis system status in patients with uterine fibroids, including the effect of hormonal, antioxidant, and disaggregate therapy. The studies conducted allowed the authors to predict the possibility of bleeding and thromboembolic complications in patients, as well as the growth of uterine fibroids, to timely correct hemostasis and improve the treatment results in patients with this pathology.