[琥珀酸盐对大鼠海马存活切片谷氨酸能突触传递有效性的影响]。

Neirofiziologiia = Neurophysiology Pub Date : 1992-01-01

V I Malakhova, O V Godukhin, M N Kondrashova

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引用次数: 0

摘要

研究了琥珀酸钠对海马残片Schaffer侧突触谷氨酸传递效率和高频刺激引起的增强状态持续时间的影响。结果表明，在大鼠断头前30分钟给予琥珀酸钠(50 mg/kg / p)可稳定大鼠海马CA1区谷氨酸的传递，并延长其增强状态的持续时间。

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[Influence of succinate on the effectiveness of glutamatergic synaptic transmission in surviving slices of rat hippocampus].

Sodium succinate has been studied for its influence on the efficiency of glutamate transmission in the Schaffer collateral synapses and duration of its potentiation state caused by high-frequency stimulation in surviving hippocampal slices. It is shown that administration of sodium succinate (50 mg/kg i. p.) to rats 30 min prior to decapitation stabilizes glutamate transmission in field CA1 of the rat hippocampal slices and increases duration of its potentiation state.

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Neirofiziologiia = Neurophysiology

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