分子生物学的确定性布尔网络(DBN)建模:DNA复制

J. W. Yeol, W. Samarrai, I. Barjis, Y. S. Ryu
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引用次数: 0

摘要

本文介绍了一种新的生物过程建模工具——中心法则。确定性布尔网络(DBN)被用作整个过程的建模工具,它使我们能够随意模拟、分析和操作(在将来)。从DNA到蛋白质通过RNA是最著名的生物过程之一,有时被称为中心法则。大多数生物过程是确定的,由非常精确的指令(包括控制方向)控制。这两个共同的事实告诉我们,表达和分析生物数据流是理解生物过程的关键。因此,建模过程易于理解,并且可以作为模拟器实现,以便学生在课堂上理解;分析和预测研究人员在不久的将来的过程。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Deterministic Boolean networks (DBN) modeling of molecular biology: DNA replication
In this paper, we introduce a new method of modeling tool for a biological process -central dogma. The deterministic Boolean Network (DBN) is used as a modeling tool of the whole process, which enables us to simulate, analyze, and manipulate (in the future) at our disposal. From DNA to protein via RNA is the one of most well-known biological process, sometimes called central-dogma. Most of biological processes are deterministic and ruled by very precise commands, including control directions. These two common facts tell that it is the key in understanding biological processes to represent and analyze the flow of data of biology. As a result, the modeled process is easy to understand and to be implemented as a simulator to make students understood in classes; analyze and predict the process for researchers in near future.
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