黑色素瘤辅助治疗引起的免疫检查点心肌炎

Global Clinical Case Reports Pub Date : 2020-12-31 DOI:10.31487/J.GCCR.2020.01.05

J. Dasher, Lavanya Kondapalli, C. Lenneman

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引用次数: 0

摘要

免疫检查点抑制剂(ICIs)是许多转移性癌症的有效治疗方法，现在被用作许多III期癌症的辅助治疗，以降低复发的高风险。ICIs可以激活患者自身的t细胞来对抗癌症，但在某些情况下，可能会发生许多器官炎症的免疫相关不良事件(irAEs)。罕见的心肌炎病例已被报道。需要更多的数据来提高我们监测、诊断和治疗急性脑梗死的能力。

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Immune Checkpoint Myocarditis from Adjuvant Treatment of Melanoma

Immune checkpoint inhibitors (ICIs) are effective therapy for many metastatic cancers and are now being used as adjuvant treatment for many stage III cancers to reduce the high risk of reoccurrence. ICIs activate a patient’s own T-cells to fight cancer, but in some cases, immune-related adverse events (irAEs) with inflammation of many organs can occur. Rare cases of myocarditis have been reported. More data is needed to improve our ability to monitor, diagnose and treat irAEs.

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Global Clinical Case Reports

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