[重症肌无力患者血清环核苷酸酸的研究]。

Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry Pub Date : 1992-12-01

J Z Xu

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引用次数: 0

摘要

应用125I-RIA法测定100例重症肌无力患者血清cAMP和cGMP水平。结果显示，患者cAMP和cGMP明显高于对照组(P < 0.001)。其中33例患者在使用抗胆碱酯酶药物和强的松后，cAMP和cGMP水平明显降低。根据我们的研究，我们推测MG患者存在环核苷酸代谢紊乱，cAMP可能在MG发病中起调节作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[A study of cyclic nucleotide acids in the serum in patients with myasthenia gravis].

The levels of cAMP and cGMP in serum of 100 patients with myasthenia gravis have been measured by 125I-RIA. The results showed that cAMP and cGMP were higher in the patients than in the controls significantly (P < 0.001). In 33 cases of these patients after using anticholinesterase drugs and prednisone, the levels of cAMP and cGMP reduced significantly. According to our study, we presumed that there would be cyclic nucleotide acid metabolic disturbances in patients with MG and cAMP might play a regulatory role in morbidity of MG.

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Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry

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