[口蹄疫病毒结构多肽的电生理特性]

A P Ponomarev, L P Soboleva, O G Andreeva, N A Bodina, V L Uziumov
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引用次数: 0

摘要

介绍了分离FMDV结构多肽的方法,并对其进行了电泳和电聚焦分析。测定了FMDV结构多肽蛋白外壳的等电点值及其对应的电势值。基于叠加原理确定了FMDV血清型病毒粒子结构的相似性和差异性,其特征是相对表面值落在不同的多肽上。FMDV已被证明具有不同值的总结负电荷。电荷取决于病毒的类型,是病毒在环境中的抗性的决定条件。在系统方法的基础上提出了FMDV的图形模型,该模型反映了病毒粒子结构中电荷分布的偶极子特征,与基于二十面体对称建立的病毒模型一致。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[The electrophysiological properties of the structural polypeptides of the foot-and-mouth-disease virus].

The methodological approaches of isolation of preparations of FMDV structural polypeptides to analyse them by the electrophoresis and electro-focussing methods are presented. The value of isoelectric points of protein coat of FMDV structural polypeptides and corresponding them values of electric potential are determined. The similarity and differences of FMDV serotypes, characterized by the value of relative surface, falling on separate polypeptides, are determined for the virion structure on the basis of superposition principle. FMDV has been shown to possess the summarized negative charge of different values. The charge depends on the virus type and it is a determining condition for viruses resistance in environment. A graphical model of FMDV is suggested on the basis of systemic approach and it reflects the dipole character of electric charge distribution in virion structure and agrees with the virus model, built on the basis of icosahedron symmetry.

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