基于嵌入种族推理的DNA图谱匹配模糊逻辑系统

R. Hartono, M. R. Widyanto, N. Soedarsono
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引用次数: 4

摘要

本文提出了一种利用简单模糊逻辑系统(FlS)进行概率推理的新方法,特别是DNA图谱匹配算法中的种族信息。该方法利用等位基因标记的分布概率密度函数作为FlS中的隶属度函数,可以快速、简便地判断两个DNA图谱之间的种族相似性。利用从印度尼西亚各民族获得的数据对该技术进行了测试,并取得了令人鼓舞的结果,能够表明一个民族内部的民族相似性得分较高,而民族之间的相似性得分较低。但是,需要进一步的研究来进一步改进模型,保证模型的正确性和准确性,特别是由于数据的判别性不强。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fuzzy logic System for DNA Profile Matching with Embedded Ethnic Inference
This paper proposes a novel technique to do probabilistic inference by using simple Fuzzy logic System (FlS), especially ethnic information in DNA profile matching algorithm. By using the allele marker’s distribution probability density function as the membership function in the FlS, the new technique makes it possible to tell the ethnic similarity between two DNA profiles in a fast and simple way. A data acquired from ethnic groups of Indonesia is used to test the technique and produced promising result, being able to indicate higher ethnic similarity score within an ethnic group and lower similarity between ethnic groups. However, further research is needed to further improve the model and warrant the correctness and accuracy, especially because the data is not very discriminative.
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