Arthur dos Santos Sena, Adolpho de Barros e Silva de Oliveira, Clara de Andrade Pontual Peres, Duílio Cabral da Costa Neto, Victor Soare Gomes da Silva, César Freire de Melo Vasconcelo, Wolfgang William Schmidt Aguiar
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Thoracic Plasmablastic Lymphoma in an Elderly Immunocompetent Patient
Plasmablastic Lymphoma (PBL) is a rare but extremely aggressive type of non-Hodgkin’s Lymphoma; it is commonly associated with HIV infection, with an incidence of approximately 2.6% among lymphomas in HIV-positive patients. Less frequently, it can also be seen in patients with other immunodeficiencies. The most commonly reported sites of PBL involvement are the oro-nasal cavity and the digestive tract. Its cellular and molecular behavior pose a significant therapeutic challenge, since it is classified as a chemoresistant neoplasm, thus its associated prognosis is usually not favorable. Due to its rarity, there are no well-established protocols for the therapeutic management of patients with this diagnosis. In the present study, we report a case of a thoracic PBL in an HIVnegative patient without other immunodeficiencies, diagnosed by surgical biopsy performed via video-assisted thoracoscopic surgery. Few cases in the literature report this type of neoplasm in immunocompetent patients. 2. Objective
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