Fetal hemoglobin rich cell therapy to combat adult anemia

Since the first hematopoietic stem cell transplantation in 1989 to treat Fanconi’s anemia, research in cord blood transplantation is currently and predominantly focused on exploiting only the 0.01% of the cord blood component rich in progenitor and stem cells [1]. The rest is often thrown away in the trash or incinerator as biological waste. Since, 1999 the paradigm changed and more and more research is now focused on utilizing the 99.9% of the cord blood and its cellular component. Bhattacharya et al., has reported the first successful HLA randomized, cord blood transfusion in more than 1000 patients suffering from severe anemia at the backdrop of different diseases.