基于金属屏蔽激光二极管和电化学修饰微电极的主动神经电极的低噪声光遗传学研究

2022 IEEE International Flexible Electronics Technology Conference (IFETC) Pub Date : 2022-08-21 DOI:10.1109/IFETC53656.2022.9948437

Minghao Wang, Minyi Jin, Fan Ye, Jiahui Xu, Bowen Ji, Yin Chen, Yuhua Cheng, Gaofeng Wang

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引用次数: 0

摘要

本文报道了一种带有金属屏蔽激光二极管(LD)和电化学修饰微电极的主动神经光电极。与现有技术相比，本研究首次将电磁屏蔽、瞬态脉冲整形和界面修饰结合起来，将刺激引起的噪声(包括电磁干扰、光伏噪声和光电化学噪声)的幅度降低到50微伏以下。所提出的神经光极在低噪声、高信噪比的神经记录和刺激方面具有广阔的应用前景。

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An Active Neural Optrode With Metal Shielding Laser Diode and Electrochemical Modified Microelectrodes for Low Noise Optogenetics

This paper reports an active neural optrode with metal shielding laser diode (LD) and electrochemical modified microelectrodes. Compared to state of the art, for the first time, this work combines electromagnetic shielding, transient pulse shaping and interface modification to reduce the amplitude of stimulus-induced noise, including electromagnetic interference, photovoltaic noise and photoelectrochemical noise, to less than 50 microvolts. The proposed neural optrode has broad prospects in the application of neural recording and stimulation with low noise and high signal-to-noise ratio.

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2022 IEEE International Flexible Electronics Technology Conference (IFETC)

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