Chengxiao Zhang, Y. Mu, Ye Zhuo, Taihua Li, F. Jin, Chun-Zhin Jin, Hyung-Gwan Lee, Long Jin
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Utilizing Bacteria-Derived Components for Cancer Immunotherapy
Bacteria-related cancer immunotherapy, because of its mechanisms and useful applications in the induction of anti-tumor immunity, has gained substantial attention in recent decades. Bacteria can enable targeting of tumors, and specifically can colonize the core tumor area. Because they contain many pathogen-associated molecular patterns—which efficiently stimulate immune cells, even within microenvironments that suppress anti-tumor immunity—bacteria boost immunological recognition leading to the destruction of malignant cells. This Editorial highlights various bacteria with immunotherapeutic effects and their by-products used as immunotherapeutics.
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