{"title":"增强光二嗪介导的肿瘤光动力治疗","authors":"D. Vassiliev, A. N. Stukov","doi":"10.1117/12.640048","DOIUrl":null,"url":null,"abstract":"Chlorine E6 derivative \"Photoditazine\" mediates photodynamic therapy (PDT) of tumours more effectively at higher doses. Both local and systemic effects were found in vivo. Synchronous PDT and selective distant laser hyperthermia (HT) are not advantageous. Excessive PDT and HT regimens leading to tumour necrosis increase the risk of tumour generalization.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"74 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Enhancing photoditazine-mediated photodynamic therapy of tumours\",\"authors\":\"D. Vassiliev, A. N. Stukov\",\"doi\":\"10.1117/12.640048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chlorine E6 derivative \\\"Photoditazine\\\" mediates photodynamic therapy (PDT) of tumours more effectively at higher doses. Both local and systemic effects were found in vivo. Synchronous PDT and selective distant laser hyperthermia (HT) are not advantageous. Excessive PDT and HT regimens leading to tumour necrosis increase the risk of tumour generalization.\",\"PeriodicalId\":219206,\"journal\":{\"name\":\"Current Research on Laser Use in Oncology\",\"volume\":\"74 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-08-08\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Research on Laser Use in Oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.640048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Research on Laser Use in Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.640048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Enhancing photoditazine-mediated photodynamic therapy of tumours
Chlorine E6 derivative "Photoditazine" mediates photodynamic therapy (PDT) of tumours more effectively at higher doses. Both local and systemic effects were found in vivo. Synchronous PDT and selective distant laser hyperthermia (HT) are not advantageous. Excessive PDT and HT regimens leading to tumour necrosis increase the risk of tumour generalization.
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