通过改变电极几何形状提高四电极聚焦阻抗法在肺部的深度灵敏度

M. Mobarak, K. S. Rabbani
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引用次数: 0

摘要

生物电阻抗在肺部疾病的检测和诊断方面具有特别重要的意义,特别是在低收入和中等收入国家。一种使用四个电极的古老的简单技术被称为“四极阻抗测量(TPIM)”,但它不能定位特定的感兴趣区域。达卡大学的一个研究小组发明了一种名为“聚焦阻抗法(FIM)”的新技术,可以在局部感兴趣的区域内提供高灵敏度。以前的FIM是从胸腔的一侧使用的,这只能从浅的深度获得相当有限的肺信息。为了从肺部的深层区域获得信息,达卡大学的同一个小组提出了一种新的FIM电极配置,将两个电极放在胸腔的前部和后部,在一个水平面上。预计深度敏感性的程度将取决于电极两侧的分离程度。电极宽度也可能有影响。为了定量研究这些,使用COMSOL Multiphysics软件在一个圆形矩形体中模拟测量结果,以代表一个典型的胸腔,该胸腔充满等渗盐水。电极间距分别为5cm、10cm、15cm和20cm,电极宽度分别为0.15cm、1cm和3cm。这项工作支持了FIM电极的新配置,因为这种方法在肺的整个深度都提高了灵敏度,对于横截面为33cm26cm的胸腔,电极间距在10cm和15cm之间将获得最佳结果。就电极宽度而言,所研究的电极并没有产生任何显著差异,然而,最小的(0.15厘米)电极的效果似乎略好一些。孟加拉国医学物理杂志Vol.15 no . 2022 P . 43-54
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Improving Deep Sensitivity of Four-Electrode Focused Impedance Method In Lungs by Varying Electrode Geometries
Bio-Electrical impedance is of special interest in the detection and diagnosis of lung problems, particularly in the low and medium income countries. An age old simple technique employing four electrodes is known as ‘Tetra Polar Impedance Measurement (TPIM)’ but it cannot localize a particular zone of interest region. A new technique named as ‘Focused Impedance Method (FIM)’ was innovated by a Dhaka University group which gives high sensitivity in a localized zone of interest. Previously FIM was used from one side of the thorax which gave a rather limited information from the lungs, from shallow depths only. In order to get information from deeper regions of the lungs a new configuration of electrodes for FIM was proposed by the same group at Dhaka University which placed two electrodes at the front and two electrodes at the back of the thorax in a horizontal plane. It is expected that the degree of depth sensitivity would depend on electrode separation on both the sides. The electrode width may also have an effect. In order to study these quantitatively, COMSOL Multiphysics software was used to simulate the measurements in a rounded rectangular volume to represent a typical thorax, which was filled with isotonic saline. Electrode separations of 5cm, 10cm, 15cm and 20cm were studied while electrode widths studied were 0.15cm, 1cm and 3cm. The work supported the proposed new configuration of electrodes for FIM in that this method gives enhanced sensitivity throughout the depths of a lung and that for a thorax with a cross section of 33cm26cm, an electrode separation between 10cm and 15cm would give optimum results. For electrode width, the ones studied did not give any significant difference, however, the smallest (0.15cm) one appeared to give slightly better results. Bangladesh Journal of Medical Physics Vol.15 No.1 2022 P 43-54
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