A. Osmolovsky, A. Shestakova, D.Ye. Surkova, R. Lehotská, E. Piecková
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引用次数: 0
摘要
研究了5种微曲霉对人止血蛋白的水解活性的多样性。对于每个菌株，缺乏类似于止血蛋白酶的活性-凝血酶，纤溶酶，Xa因子，尿激酶和蛋白C。此外，对命名的蛋白酶的前体没有激活活性。在青花蒿中发现了高活性的蛋白酶(58、52 utr)和特异的抗brinogen酶。A. athecius, A. caespitosus和A. wentii在酸性pH下具有蛋白水解能力。
INVESTIGATION OF NEW ASPERGILLUS STRAINS AS PRODUCERS OF HEMOSTATICALLY ACTIVE PROTEASES
For ve species of Aspergillus micromycetes, the diversity of proteolytic activities against human hemostasis proteins was assessed. For every strain, absence of activities similar to hemostatic proteases - thrombin, plasmin, factor Xa, urokinase, and protein C was shown. In addition, no activating activities towards precursors of the named proteases were demonstrated. For A. glaucus, proteases of high activity (58,52 Utyr) and speci city against brinogen were found. A. athecius, A. caespitosus и A. wentii, were capable of proteolysis at acidic pH.
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