铅神经毒性研究进展

Yumeng Li, Danni Huang, Liangrong Li, Rongna Rao, Qiaoyan Wei, Yi Sun
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引用次数: 0

摘要

:铅是一种强毒性金属,可通过富集在生物体相应的靶器官中沿食物链不断积累,从而对机体的生长发育造成损害。目前的研究普遍认为铅对人体的损害没有阈值,即任何剂量的铅都可能对人体产生有害影响,因此铅暴露引起的神经毒性仍受到广泛关注。本文就铅暴露现状、不同水平铅对人体、细胞和动物的神经毒性研究及易感标志物进行综述,以期为今后进一步开展铅神经毒性研究和制定合理的防治措施提供科学依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Research Progress in Lead Neurotoxicity
: Lead is a powerful toxic metal that can accumulate continuously along the food chain in the corresponding target organs of organisms through enrichment, thereby causing damage to the growth and development of the body. Current research generally believes that there is no threshold for the damage caused by lead to the human body, that is, any dose of lead may have harmful effects on the human body, so the neurotoxicity caused by lead exposure still receives widespread attention. This article summarizes the current situation of lead exposure, studies on different levels of lead neurotoxicity in humans, cells, and animals, and susceptibility markers, hoping to provide scientific basis for further research on lead neurotoxicity and formulating reasonable prevention and control measures in the future.
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