犹他电极阵列的同步阻抗测量:一种有限元分析方法

Elena della Valle, J. Weiland
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引用次数: 0

摘要

用于记录或刺激神经系统的高计数微电极阵列具有恢复因疾病或损伤而丧失的功能的潜力。跟踪电极的特性和随时间的变化对于可靠性评估和人为实施至关重要。目前的阻抗测量方法是手动的,通常限制在单一频率(1khz)。通道按顺序求值。当存在100个或更多通道时,该过程可能会变得非常耗时。本文采用有限元方法对犹他电极阵列(UEA)中100个电极同时测量阻抗的影响进行了研究。我们模拟了植入大脑的UEA的恒电位阻抗谱。模拟使用25 mV激励电压,在1 Hz到10 MHz的频率范围内应用于共同参考。每个单独的电极通道保持在地电位,并测量通过每个通道的电流以确定阻抗。由于电场线在电极组织界面附近拥挤,同时测量电极时比测量单个电极时阻抗更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simultaneous impedance measurements of the Utah electrodes array : A finite element method analysis
High-count micro-electrode arrays for the recording or stimulation of the nervous system have the potential to restore function lost to disease or injury. The tracking of the electrode characteristics and changes over time becomes crucial for reliability evaluation and human implementation. Current approaches to impedance measurement are manual and often restricted to a single frequency (1 kHz). Channels are evaluated serially. When 100 or more channels are present, the process can become time-consuming. In this paper, we use finite element method (FEM) modeling for studying the impact of simultaneous impedance measurement of 100 electrodes of a Utah Electrode Array (UEA). We simulate potentiostatic impedance spectroscopy of a UEA implanted in the brain. The simulations have been performed using a 25 mV excitation voltage, applied to a common reference, at frequency range from 1 Hz to 10 MHz. Each individual electrode channel is held at ground potential and the current through each channel is measured to determine impedance. Higher impedance has been found when measuring the electrodes simultaneously versus measurement of a single electrode, due to crowding of electric field lines near the electrode tissue interface.
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