埃及亚历山大省犬患糖尿病的患病率、临床情况和危险因素

Meray Mikhaiel, M. Nasr, N. Bakeir, N. Beder, Besheer G. Elshafey, A. Saleh
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摘要

本研究旨在确定埃及亚历山大省犬中糖尿病的患病率、临床表现、并发症和危险因素。2020年11月至2021年4月期间,来自亚历山大省兽医管理局的代表15个品种的139只狗参与了这项研究。在完成临床检查并填写预先设计的问卷后,对所有动物进行随机血糖(RBG)测试。高RBG水平的患者接受全血检查(CBC)、肝肾功能和HbA1c。选择50只年龄、性别、品种和管理方式相似的狗作为对照组,进行同样的分析。研究犬的糖尿病患病率为7.2%。所有糖尿病患者都患有多饮和多尿,60%的糖尿病患者患有多食症,80%的糖尿病患者体重减轻。DM对体温、呼吸频率、贫血、肝酶和血小板计数无显著影响,但脉搏率显著升高。糖尿病对眼睛的影响很大,因为80%的糖尿病狗患有白内障。它对总白细胞计数和肾功能有显著影响,其中70%的糖尿病患者肾功能受损。在与糖尿病发生相关的危险因素分析中,只有品种被确定为cDM(犬糖尿病)的潜在危险因素。因此,必须把cDM作为一种重要的、并不罕见的狗病来关注,我们需要提高兽医和狗主人对cDM的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence, Clinical Picture, and Risk Factors Associated with Diabetes Mellitus in Dogs in Alexandria Governorate, Egypt
This study was conducted to determine the prevalence, clinical picture, complications, and risk factors associated with Diabetes Mellitus in dogs in Alexandria governorate, Egypt. One hundred and thirty-nine dogs representing fifteen breeds from the Directorate of Veterinary Medicine in Alexandria governorate were involved in the study between November 2020 and April 2021. After a thorough clinical examination and filling out a pre-designed questionnaire, random blood glucose (RBG) test was performed for all animals. Those with high RBG levels were subjected to a complete blood picture (CBC), liver and kidney functions, and HbA1c. A control group of 50 dogs of similar age, sex, breed, and management was selected and subjected to the same analyses. The prevalence of DM among the studied dogs was 7.2 %. All diabetics suffered from polydipsia and polyuria, while 60% suffered from polyphagia and 80% suffered from weight loss. No significant impact of DM on temperature, respiratory rate, anaemia, liver enzymes and platelets count, but there was a significant increase in pulse rate. There was a significant impact of DM on eyes as 80% of the diabetic dogs suffered from cataracts. It had a significant impact on total leucocyte count and on the renal function, where 70 % of the diabetics had impaired renal functions. Regarding the risk factor analysis associated with the occurrence of DM, only breed has been identified as a potential risk factor for cDM (canine diabetes mellitus). So, a spotlight must be thrown on cDM as an essential and not uncommon dog’s disease, and we need to raise awareness of cDM among veterinarians and dogs’ owners.
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