细胞、组织和器官纳秒脉冲暴露的计算机评价

Conference Record of the 2006 Twenty-Seventh International Power Modulator Symposium Pub Date : 2006-05-14 DOI:10.1109/MODSYM.2006.365295

T. Gowrishankar, A. Esser, K. Smith, J. Weaver

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引用次数: 0

摘要

我们开发了一个集成了宏观和微观剂量学模型的硅框架，并结合了生物物理机制模型来估计暴露于纳秒电脉冲导致的生化变化。这种方法提供了细胞、局部组织区域和器官内电导变化和生化释放/摄取的估计

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In Silico Assessment of Nanosecond Pulse Exposures of Cells, Tissues and Organs

We have developed an in silico framework that integrates macro- and microdosimetry models, and incorporates biophysical mechanism models to estimate biochemical change resulting from exposure to nanosecond electrical pulses. This approach provides estimates of conductance changes and biochemical release/uptake within cells, local tissue regions and organs

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Conference Record of the 2006 Twenty-Seventh International Power Modulator Symposium

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