{"title":"Gambaran Penggunaan Fibrinolitik Pada Pasien Stemi (St-Segment Elevation Myocardial Infarction) Di Rumah Sakit “X” Di Kota Tarakan","authors":"Marizka Anggreani, Irma Novrianti, Sari Wijayanti","doi":"10.32382/mf.v18i1.2450","DOIUrl":null,"url":null,"abstract":"Although non-communicable, cardiovascular diseases cause the highest global mortality rate, i.e., 16.6%. Tarakan is one of the cities in the province of North Kalimantan. Based on the results of the 2018 Riskesdas, the highest prevalence of coronary heart disease (CHD) is in the province of North Kalimantan. Cardiac catheterization laboratory facilities are not yet available, so fibrinolytic therapy is still the first line of reperfusion therapy for STEMI. This research is aimed at analyzing fibrinolytics administration at “X” Hospital in Tarakan. This is descriptive retrospective research to examine fibrinolytics administration in 39 in-patients with STEMI at “X” Hospital in Tarakan, on January 2017-December 2018. The fibrinolytic agents used were fibrin-specific and non-fibrin-specific. Alteplase was administered to 13 patients (33.33%). Alteplase was administered in three dosages, i.e., 15 mg administered in a bolus in the early stage, 50 mg administered by an intravenous infusion for 30 minutes, and 35 mg administered for 60 minutes. 26 patients (66.66%) were administered Streptokinase. Streptokinase was intravenously administered at 1.5 million IU in 100 mL of salt solution for 30-60 minutes. The result demonstrates that the non-fibrin-specific agent, administered to 26 patients (66.66%), was mostly used here.","PeriodicalId":190256,"journal":{"name":"Media Farmasi","volume":"89 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Media Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32382/mf.v18i1.2450","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Gambaran Penggunaan Fibrinolitik Pada Pasien Stemi (St-Segment Elevation Myocardial Infarction) Di Rumah Sakit “X” Di Kota Tarakan
Although non-communicable, cardiovascular diseases cause the highest global mortality rate, i.e., 16.6%. Tarakan is one of the cities in the province of North Kalimantan. Based on the results of the 2018 Riskesdas, the highest prevalence of coronary heart disease (CHD) is in the province of North Kalimantan. Cardiac catheterization laboratory facilities are not yet available, so fibrinolytic therapy is still the first line of reperfusion therapy for STEMI. This research is aimed at analyzing fibrinolytics administration at “X” Hospital in Tarakan. This is descriptive retrospective research to examine fibrinolytics administration in 39 in-patients with STEMI at “X” Hospital in Tarakan, on January 2017-December 2018. The fibrinolytic agents used were fibrin-specific and non-fibrin-specific. Alteplase was administered to 13 patients (33.33%). Alteplase was administered in three dosages, i.e., 15 mg administered in a bolus in the early stage, 50 mg administered by an intravenous infusion for 30 minutes, and 35 mg administered for 60 minutes. 26 patients (66.66%) were administered Streptokinase. Streptokinase was intravenously administered at 1.5 million IU in 100 mL of salt solution for 30-60 minutes. The result demonstrates that the non-fibrin-specific agent, administered to 26 patients (66.66%), was mostly used here.