The Range of European Nutritional Practice – Inspiring and on the Point

Obesity is a global health problem, due to its high prevalence and strong association with hypertension, coronary heart disease, stroke, and other metabolic disorders. In mammals, energy balance is maintained via a homeostatic system involving both peripheral and central systems – changes in body weight reflect an unbalanced energetic state. Studies confirmed that a clear sexual dimorphism exists in how the brain regulates energy homeostasis and in the resulting metabolic adaptation to diet-induced obesity. There is growing evidence showing that postmenopausal females are more prone to develop obesity in comparison to premenopausal females. Multiple studies have established a link between the vulnerability to develop metabolic disturbances with reproductive decline. This suggests that estrogens play a protective role in this context. The most imKomp Nutr Diet 2023;2:44–47 DOI: 10.1159/000530195