老年多病合并HIV感染患者弥散性肺病(临床一例)

E. Yakovleva
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摘要

播散性肺部疾病在各种病因、发病机制和形态学上具有相似的非特异性表现。肺播散是x射线的概念,在x光片上没有特定疾病固有的病理症状,因此,在实际临床实践中,肺播散的鉴别诊断是医生的特权。以肺部播散为表现的疾病可分为感染性原因的播散(肺结核、hiv相关的播散、真菌病变)、恶性肺病变(癌病、癌性淋巴管炎)、心源性播散和肺间质性疾病。近年来,变应性间质性肺疾病的发病率有所增加。在许多情况下,艾滋病毒感染患者的肺部感染性病变和免疫状态降低也具有播散性,给结核病的鉴别诊断带来困难。本文报道一例肺囊虫性肺炎伴肺播散综合征的hiv感染患者的x线表现。患者和医生的低依从性显示了诊断搜索的困难(一个登记为艾滋病毒10年的患者向主治医生隐瞒了他的病史,并书面拒绝接受艾滋病毒纤维支气管镜检查)。已经考虑了对所有因肺部播散性病变而入院的病人实行强制性艾滋病毒筛查的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Disseminated lung disease in elderly patient with multimorbidity and HIV infection (clinical case)
Disseminated lung diseases have similar non-specific manifestations in various etiologies, pathogenesis, and morphology. Pulmonary dissemination is the concept of X-ray, there are no pathognomonic symptoms on a radiograph that are inherent in a particular disease with pulmonary dissemination, therefore, in real clinical practice, differential diagnosis in pulmonary dissemination is the prerogative of the physician. Diseases that are manifested by pulmonary dissemination can be classified by dissemination of infectious causes (tuberculosis, HIV-associated dissemination, fungal lesions), malignant pulmonary lesions (carcinomatosis, cancer lymphangitis), cardiogenic dissemination and interstitial lung diseases. In recent years, the incidence of allergic interstitial lung diseases has increased. Infectious lesions of the lungs in patients with HIV infection and reduced immune status in many cases also have a disseminated form and cause difficulties in the differential diagnosis of tuberculosis. The article presents a clinical case of pneumocystis pneumonia in an HIV-infected patient with pulmonary dissemination syndrome on X-ray. The difficulties of the diagnostic search with low compliance of the patient and the physician are shown (a patient registered with HIV for 10 years hid this fact of his history from the attending physician and gave a written refusal to get tested for HIV fibrobronchoscopy). The possibility of introducing compulsory HIV screening for all patients admitted to the hospital with disseminated processes in the lungs has been considered.
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