一个完全集成的闭环神经调节SoC,具有无线电源和双向数据遥测,用于实时控制人类癫痫发作

Cheng-Hsiang Cheng, Ping-Yuan Tsai, Tzu-Yi Yang, Wan-Hsueh Cheng, Ting-Yang Yen, Zhicong Luo, Xin-Hong Qian, Zhi-Xin Chen, T. Lin, Wei-Hong Chen, Wei-Ming Chen, Sheng-Fu Liang, Fu-Zen Shaw, Cheng-Siu Chang, F. Shih, Y. Hsin, Chen-Yi Lee, M. Ker, Chung-Yu Wu
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引用次数: 20

摘要

本文提出了一种用于人类癫痫发作控制的16通道闭环神经调节SoC。SoC包括一个16-ch信号采集单元、一个生物信号处理器、一个16-ch自适应刺激器和无线遥测。信号采集单元达到3.78 NEF,与刺激器共用电极。癫痫发作检测潜伏期为0.76s,并给予0.5 ~ 3ma双相电流刺激。SoC是无线供电的,通过13.56MHz的同一对线圈实现双向数据遥测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A fully integrated closed-loop neuromodulation SoC with wireless power and bi-directional data telemetry for real-time human epileptic seizure control
This paper presents a 16-channel closed-loop neuromodulation SoC for human seizure control. The SoC includes a 16-ch signal acquisition unit, a bio-signal processor, a 16-ch adaptive stimulator, and wireless telemetry. The signal acquisition unit achieves 3.78 NEF and shares electrodes with stimulator. The seizure detection latency is 0.76s and delivered 0.5–3mA biphasic current stimulation. The SoC is powered wirelessly and bidirectional data telemetry is realized through the same pair of coils in 13.56MHz.
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