描绘放射诊断的灰色地带——放射组学——放射组学的新方向——虚拟活检

Gayathri Sanjay, Lekha Shreedhara, K. Guttal, K. Nandimath, K. Burde
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引用次数: 0

摘要

组学是构成生物学各个分支的科学分支。它通过对生物分子的集体表征和量化来确定生物体的结构、功能和动力学。诊断成像模式已达到其发展的顶峰,导致数据库的复杂性和容量升级。这为一种称为放射组学的成像诊断新方法奠定了基础。放射组学是指从医学成像中获取模糊数据,并在肿瘤学中应用,以增强诊断和预测,帮助临床决策,目的是提供精准医疗。放射组学的主要应用是在肿瘤学中增加诊断和预后,从而改善临床决策。因此,提供精准医疗的成功率更高,因为它有助于从x光片中获取和强调模糊数据。放射科医生以及数据和成像科学家代表了放射组学跨学科工作流程的组成部分。它包括一步一步的肿瘤分割、图像预处理、特征提取、分析、模型开发和验证的综合过程。由于这种最高的潜力,它可以作为临床和研究目的的最终解决方案。本文强调放射组学在定义、标准化和培养临床医生可访问的庞大数据库中的作用。这将使他们能够深入了解每一个特定的病例,最终在世界各地具有可比治疗或临床试验概况的患者之间建立联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Delineating the grey areas in radiodiagnosis-Radiomics a new way forward Radiomics- A virtual biopsy
Omics are the branches of science which constitute the various affiliates of biology. It determines the structure, function and dynamics of organisms through collective characterization and quantification of biological molecules. The diagnostic imaging modalities have peaked in their advancements, leading to escalated complexity and volume of database. This has ushered the foundation of a novel approach to imaging diagnosis called radiomics. Radiomics refers to the accentuation and procurement of ambiguous data from medical imaging and has been applied within oncology to enhance diagnosis and prognostication, aiding in clinical decision, with the aim of delivering precision medicine. The chief application of radiomics is in oncology to augment diagnosis and prognosis, thereby improving clinical decision. Consequently, the success rates for delivering precision medicine is higher as it facilitates the procurement and accentuation of ambiguous data from rradiographs. Radiologists as well as data and imaging scientists represent an integral part of the interdisciplinary workflow of radiomics. It involves a comprehensive process of step by step tumour segmentation, image pre-processing, feature extraction, analysis, model development, and validation. By this paramount potentiality, it serves as a definitive solution for both clinical and research purposes. This paper highlights the role of radiomics in defining, standardization, and cultivating vast databases accessible to clinicians. This will empower them to tap into every particular case, eventually creating a link among patients having comparable profiles for treatments or clinical trials all over the world.
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