Sathvika Mudigonda, F. Oloumi, Kalyana M. Katta, R. Rangayyan
{"title":"视网膜眼底图像中糖尿病视网膜病变新生血管的分形分析","authors":"Sathvika Mudigonda, F. Oloumi, Kalyana M. Katta, R. Rangayyan","doi":"10.1109/EHB.2015.7391551","DOIUrl":null,"url":null,"abstract":"This study focuses on detecting and classifying neovascularization caused by proliferative diabetic retinopathy (PDR) in retinal fundus images. Image processing methods were applied to detect retinal vessels. A fractal analysis approach based on the box-counting method was used to quantify vascular patterns in normal and abnormal cases showing neovascularization near the optic disk (NVD). Ten images including five normal cases and five neovascularization cases were analyzed. The mean fractal dimension obtained for the NVD cases was 1.66 compared to the mean value of 1.52 for the normal cases. The statistical significance of the difference was high, with a p-value of 0.0088. The results show promise for use in detecting neovascularization in retinal images caused by PDR.","PeriodicalId":291361,"journal":{"name":"2015 E-Health and Bioengineering Conference (EHB)","volume":"20 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2015-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Fractal analysis of neovascularization due to diabetic retinopathy in retinal fundus images\",\"authors\":\"Sathvika Mudigonda, F. Oloumi, Kalyana M. Katta, R. Rangayyan\",\"doi\":\"10.1109/EHB.2015.7391551\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study focuses on detecting and classifying neovascularization caused by proliferative diabetic retinopathy (PDR) in retinal fundus images. Image processing methods were applied to detect retinal vessels. A fractal analysis approach based on the box-counting method was used to quantify vascular patterns in normal and abnormal cases showing neovascularization near the optic disk (NVD). Ten images including five normal cases and five neovascularization cases were analyzed. The mean fractal dimension obtained for the NVD cases was 1.66 compared to the mean value of 1.52 for the normal cases. The statistical significance of the difference was high, with a p-value of 0.0088. The results show promise for use in detecting neovascularization in retinal images caused by PDR.\",\"PeriodicalId\":291361,\"journal\":{\"name\":\"2015 E-Health and Bioengineering Conference (EHB)\",\"volume\":\"20 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2015 E-Health and Bioengineering Conference (EHB)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/EHB.2015.7391551\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2015 E-Health and Bioengineering Conference (EHB)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/EHB.2015.7391551","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Fractal analysis of neovascularization due to diabetic retinopathy in retinal fundus images
This study focuses on detecting and classifying neovascularization caused by proliferative diabetic retinopathy (PDR) in retinal fundus images. Image processing methods were applied to detect retinal vessels. A fractal analysis approach based on the box-counting method was used to quantify vascular patterns in normal and abnormal cases showing neovascularization near the optic disk (NVD). Ten images including five normal cases and five neovascularization cases were analyzed. The mean fractal dimension obtained for the NVD cases was 1.66 compared to the mean value of 1.52 for the normal cases. The statistical significance of the difference was high, with a p-value of 0.0088. The results show promise for use in detecting neovascularization in retinal images caused by PDR.