Multiple sclerosis in children and adolescents

Multiple sclerosis in children and adolescents (PedMS) presents a significant challenge both in diagnostic and therapeutic terms. Developmental specificities are the cause of numerous differences in PedMS in relation to the adult form of multiple sclerosis (AoMS). In the field of basic and clinical neurological research, researchers' opinions are conflicted creating many questions and dilemmas, which suggest that PedMS is distinguished as a different and specific disease compared to AoMS. Having in mind the ability of the developing brain to compensate for damage, leading to partial recovery, the imperative of adequate treatment is the early diagnosis and early administration of immunomodulatory therapy.