弹性假黄瘤中的弹性组织。心内膜病变的超微结构研究。

Archives of pathology Pub Date : 1975-12-01
M Akhtar, H Brody
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引用次数: 0

摘要

一名56岁女性患有弹性假性黄瘤(PXE)。心内膜超微结构显示胶原生成和弹性生成增加。新形成的弹性纤维形态正常,但有明显的钙化倾向。钙化区域的内部结构基本上与相邻的弹性纤维的未受损伤部分相似。一些严重钙化的纤维显示出内部结构的丧失和断裂。这些发现支持了PXE的概念,即钙化涉及形态不变的弹性纤维,随后可能发生继发性退行性改变,如内部结构丧失和断裂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Elastic tissue in pseudoxanthoma elasticum. Ultrastructural study of endocardial lesions.

A 56-year-old woman had pseudoxanthoma elasticum (PXE). Ultrastructural findings in the endocardium showed increased collagenogenesis and elastogenesis. The newly formed elastic fibers appeared morphologically normal, but showed a notable propensity to become calcified. The internal structure of the calcified areas was essentially similar to that of the adjacent uninvolved portions of the elastic fibers. Some of the heavily calcified fibers showed loss of internal structure and fragmentation. These findings support the concept that in PXE, calcification involves morphologically unaltered elastic fibers that subsequently may undergo secondary degenerative changes, such as loss of internal structure and fragmentation.

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