肺嗜酸性粒细胞增多症的临床比较研究

Dr Abhijit Durge, D. Patil, Dr. Saurabh Joshi
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引用次数: 0

摘要

临床试验采用随机、单盲、比较。A组在与科希纳伽拉共餐后给予药物Kantakari ghrita,剂量为5 g,每天2次;b组在与科希纳伽拉共餐后给予药物Vidaryadi ghrita,剂量为5 g,每天2次。根据临床和实验室参数对两组进行评估。随访21 d,进行统计学分析。统计分析显示,两组患者的Ura shoola、Udar shoola、Shira shoola、Swarbheda、Swar ksheenata、Mukha shushkata、Shushka Kasan、Vega prasaktata等症状和体征得到了更好的缓解。没有观察到药物不良反应或毒性迹象,表明药物的正确制备。治疗后ESR、TLC、嗜酸性粒细胞计数明显降低。其他实验室参数保持不变,但治疗后由于嗜酸性粒细胞计数显著减少,多态性计数显著增加。Kantakari ghrita和Vidaryadi ghrita是根据samitata的文本参考而准备的。分析研究按照CCRAS《阿育吠陀制剂药典标准》的规定进行,并参考前人的工作,其他一般定量分析结果按限量和规范进行。该实验清楚地得出结论,Kantakari ghrita和Vidaryadi ghrita可能是Vataj Kasa的一种治疗方法,而不会引起任何不良药物反应,并且可能证明自己是一种强有力的解决方案。它还表明,维达雅迪ghrita是治疗肺嗜酸性粒细胞增多症的药物,因为这可以在vataj Kasa下考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
VATAJ KASA AND ITS MANAGEMENT BY VIDARYADI GHRITA AND KANTAKARI GHRITA W S R TO PULMONARY EOSINOPHILIA – A CLINICAL COMPARATIVE STUDY
Clinical trial was randomized, single blind and comparative. Group A was given the drug Kantakari ghrita in a dose of 5 g twice a day after meals with Koshna jala and Group b was given the drug Vidaryadi ghrita in a dose of 5 g twice a day after meals with Koshna jala. Both the groups were evaluated on the basis of Clinical as well as Laboratorial parameters. Follow up was taken up to 21 days and then after statistical analysis was done. Statistical analysis reveals that sign and symptoms like Ura shoola, Udar shoola, Shira shoola, Swarbheda, Swar ksheenata, Mukha shushkata, Shushka Kasan, Vega prasaktata etc are relieved much better in both the groups. No Adverse Drug Reaction or Toxicity signs have been observed which indicates proper preparation of drugs. Significant decrease was observed in ESR, TLC and Eosinophil count after treatment. Rest laboratorial parameters remained same however Polymorph count is significantly increased after treatment due to significant decrease in Eosinophil count.Kantakari ghrita and Vidaryadi ghrita were prepared accordingly to the textual reference in Samhita.. Analytical study was performed as per given in the book ‘ Pharmacopeial Standards for Ayurvedic Formulations’ by CCRAS and with reference of previous work don Other findings of general quantitive analysis were as per the limits and as per specifications. The experiment clearly concludes that Kantakari ghrita and Vidaryadi ghrita could be a remedy for Vataj Kasa without causing any Adverse Drug Reactions and may prove itself as a strong solution for unanswered infections. It also indicates that Vidaryadi ghrita be remedy for pulmonary Eosinophilia as this can be considered under vataj Kasa.
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