用于恢复失去的感觉和运动功能的微制造电极阵列

R. Normann
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引用次数: 18

摘要

使用新型微电极阵列直接与中枢和外周神经系统中的大量神经元通信的可能性,促使人们探索该技术作为恢复因疾病或创伤而失去这些功能的人的感觉和/或运动功能的手段。本文介绍了一种这样的微电极阵列,“犹他电极阵列”,以及它在1)恢复视力和2)使严重神经肌肉疾病患者更有效地与环境相互作用方面的应用。虽然这些设备尚未达到临床阶段,但正在进行的动物实验正在提供概念验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Microfabricated electrode arrays for restoring lost sensory and motor functions
The possibility of communicating directly to large numbers of neurons in the central and peripheral nervous system using new types of microelectrode arrays has motivated the exploration of this technology as a means to restore sensory and/or motor function in those who have lost these functions due to disease or trauma. This paper describes one such microelectrode array, the 'Utah Electrode Array', and its application in 1) the restoration of sight and 2) in enabling patients with severe neuromuscular disease to more effectively interact with their environment. Although these devices have not reached the clinical stage, ongoing animal experimentation is providing proof-of-concept.
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