某三级医院伊莉莎白菌脑膜炎败血症暴发调查

Pragathi Kottapalli, Chintha Deepika, S. Jyothi, Rincy Mol, Y. Sadhana, P. Chander Reddy
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引用次数: 1

摘要

研究的目的和目的:本研究的目的和目的是对AIG医院的elizabeth ethkingia脑膜炎脓毒杆菌感染患者进行前瞻性研究,并确定我院脑膜炎脓毒杆菌的可能来源。材料和方法:2021年2月在重症监护病房(icu)发现脑膜炎脓毒杆菌感染暴发。开展了一项前瞻性研究,并收集了环境监测拭子培养物以及使用形式表格的病例表临床数据,以确定与脑膜炎脓毒杆菌感染相关的可能危险因素。感染控制小组与医院管理层共同制定干预策略。结果:在2021年3月至2021年5月期间,共记录了10例脑膜炎脓毒杆菌菌血症和肺炎病例。这在COVID-19患者、ICU住院时间较长、使用多种抗生素的患者中更为常见,并与预后不良相关。从各种来源收集的监测拭子培养显示在一些icu的自来水中有脑膜炎脓毒杆菌的生长。结论:考虑到脑膜炎脓毒杆菌通常对多种抗生素耐药,且不适当的抗菌药物治疗是导致死亡的独立危险因素,早期诊断和适当的抗生素治疗对脑膜炎脓毒杆菌感染至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Outbreak investigation of Elizabethkingia meningoseptica at a tertiary care hospital
Aim and Objective of the Study: The aim and objective of this study were to do a prospective study on patients with Elizabethkingia meningoseptica infection at AIG Hospitals and to identify the possible source of E. meningoseptica in our hospital. Materials and Methods: Outbreak of infection with E. meningoseptica was identified in intensive care units (ICUs) in February 2021. A prospective study was taken up and environmental surveillance swab cultures were collected along with clinical data from case sheets using a pro forma to identify the possible risk factors associated with E. meningoseptica infection. Interventional strategies were planned by infection control team along with hospital administration. Results: A total of 10 E. meningoseptica bacteraemia and pneumonia cases were documented between March 2021 and May 2021. It was more common among patients with COVID-19, with prolonged ICU stay, and on multiple antibiotics and was associated with poor outcomes. Surveillance swab cultures collected from various sources showed growth of E. meningoseptica in the tap water of some ICUs. Conclusion: Considering that E. meningoseptica are usually resistant to multiple antibiotics and that inappropriate antimicrobial therapy is an independent risk factor for mortality, early diagnosis and adequate antibiotic treatment are vital for patients with E. meningoseptica infection.
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