褪黑素:对正常组织的抗增殖作用和保护作用，以及增强乳腺癌细胞的放射敏感性

Journal of Cell Science and Therapy Pub Date : 2016-04-25 DOI:10.4172/2157-7013.1000241

C. Campa, C. Alonso-González, Alicia González, Alicia González-González, Javier Menéndez-Menéndez, S. Cos

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引用次数: 8

摘要

褪黑素是哺乳动物体内由松果体产生的一种小的吲哚胺，它调节人类的睡眠-觉醒周期，将环境闪电的变化转化为黑暗中褪黑素的产生。这种激素有多种作用机制，包括受体依赖和受体独立的功能。在这些最后的作用中，我们可以引用褪黑素在缺血，药物毒性和电离辐射下保护细胞免受氧化应激的能力

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Melatonin: Antiproliferative Actions and Protection of Normal Tissue andEnhancement of Radiosensitivity of Breast Cancer Cells

Melatonin is a small indolamine produced in mammals by the pineal gland, which regulates the sleep-wake cycle in humans, transducing the changes of environmental lightning into a darkness production of melatonin. This hormone has several mechanisms of action involving receptor-dependent and receptor-independent functions. Among these last actions, we can cite melatonin´s ability to protect the cells from oxidative stress under ischemia, drug toxicity and ionizing radiation

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Journal of Cell Science and Therapy

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