P. Gradišnik, Andreja Osterc Koprivšek, M. Rus, T. Golli, H. Damjan
{"title":"与SARS-CoV-2感染相关的颅多神经炎1例报告","authors":"P. Gradišnik, Andreja Osterc Koprivšek, M. Rus, T. Golli, H. Damjan","doi":"10.18690/actabiomed.251","DOIUrl":null,"url":null,"abstract":"Purpose: Polyneuritis cranialis (PNC) is a less known regional variant of Guillain-Barré syndrome and has rarely been described in children. Here, we report a case of an adolescent, who became perilously ill following severe acute respiratory syndrome-coronavirus 2 infection. \nCase report: A 15-year-old boy presented with acute multiple cranial nerve palsies. The presence of GQ1b antibodies and nerve conduction studies confirmed the diagnosis of PNC. The patient was treated with plasmapheresis and intravenous immunoglobulins, but clinical improvement was gradual and very slow. \nConclusion: PNC is a rare and severe neurologic condition that can be triggered by coronavirus infection.","PeriodicalId":186880,"journal":{"name":"Acta Medico-Biotechnica","volume":"40 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Polyneuritis cranialis related to SARS-CoV-2 infection: a case report\",\"authors\":\"P. Gradišnik, Andreja Osterc Koprivšek, M. Rus, T. Golli, H. Damjan\",\"doi\":\"10.18690/actabiomed.251\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Purpose: Polyneuritis cranialis (PNC) is a less known regional variant of Guillain-Barré syndrome and has rarely been described in children. Here, we report a case of an adolescent, who became perilously ill following severe acute respiratory syndrome-coronavirus 2 infection. \\nCase report: A 15-year-old boy presented with acute multiple cranial nerve palsies. The presence of GQ1b antibodies and nerve conduction studies confirmed the diagnosis of PNC. The patient was treated with plasmapheresis and intravenous immunoglobulins, but clinical improvement was gradual and very slow. \\nConclusion: PNC is a rare and severe neurologic condition that can be triggered by coronavirus infection.\",\"PeriodicalId\":186880,\"journal\":{\"name\":\"Acta Medico-Biotechnica\",\"volume\":\"40 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-07-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Medico-Biotechnica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18690/actabiomed.251\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Medico-Biotechnica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18690/actabiomed.251","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Polyneuritis cranialis related to SARS-CoV-2 infection: a case report
Purpose: Polyneuritis cranialis (PNC) is a less known regional variant of Guillain-Barré syndrome and has rarely been described in children. Here, we report a case of an adolescent, who became perilously ill following severe acute respiratory syndrome-coronavirus 2 infection.
Case report: A 15-year-old boy presented with acute multiple cranial nerve palsies. The presence of GQ1b antibodies and nerve conduction studies confirmed the diagnosis of PNC. The patient was treated with plasmapheresis and intravenous immunoglobulins, but clinical improvement was gradual and very slow.
Conclusion: PNC is a rare and severe neurologic condition that can be triggered by coronavirus infection.