T. Rim, Sungho Kim, Kihyun Kim, Nanki Hong, Jeong-Soo Lee, Y. Jeong, M. Meyyappan, C. Baek
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Noise consideration for cancer marker detection using nanowire
In this paper, a method to extract the signal-to-noise ratio (SNR) is proposed for the Si nanowire (Si-NW) biologically-active field-effect transistors (BioFETs). We have fabricated the devices using CMOS compatible process and demonstrated specific alpha fetoprotein (AFP) detection using the monoclonal antibody of AFP. The low-frequency noise was measured to calculate the parameter. Using our method, we calculated the noise equivalent voltage and calculated the SNR. The Si-NW BioFET showed a SNR of 15.1dB. These parameters are useful indicators to evaluate FET-type sensor devices.
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