SARS-CoV-2氨基酸序列结构蛋白位置相关突变的发现

2022 12th International Congress on Advanced Applied Informatics (IIAI-AAI) Pub Date : 2022-07-01 DOI:10.1109/IIAIAAI55812.2022.00022

Kan Yonashiro, Yuichi Shimaya, Kouichi Hirata

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引用次数: 1

摘要

本文在SARS-CoV-2的氨基酸序列中发现了穗蛋白、包膜蛋白、膜蛋白和核衣壳蛋白结构蛋白位置的相关突变。这里，我们采用Shimada et al.(2012)设计的由联合熵表示的寻找相关突变的算法。我们特别关注发现的相关突变是否包含SARS-CoV-2 Delta变体的刺突蛋白替代。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Finding Correlated Mutations of Positions among Structural Proteins in SARS-CoV-2 Amino Acid Sequences

In this paper, we find the correlated mutations of positions among structural proteins of spike, envelop, membrane and nucleocapsid proteins in amino acid sequences of SARS-CoV-2. Here, we adopt the algorithm designed by Shimada et al. (2012) of finding the correlated mutations formulated by joint entropy. In particular, we focus on whether or not the found correlated mutations contains spike protein substitutions in SARS-CoV-2 Delta variant.

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2022 12th International Congress on Advanced Applied Informatics (IIAI-AAI)

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