原发性和继发性雷诺现象患者的毛细血管镜检查结果及临床特点

E. R. Tralice, M. Tamborenea, F. Romanini, M. Bejarano, A. Secco
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引用次数: 0

摘要

目的:描述原发性雷诺氏现象(PRP)和继发性雷诺氏现象(SRP)患者的视频毛细血管镜检查(VCP)结果;比较两者的人口学和临床特征。材料和方法:观察性、分析性、横断面研究。记录年龄、职业、RP发展时间、结缔组织病(CTD)及毛细血管镜特征。VCP报告为正常、非特异性或早期、活动性和晚期SD型。进行描述性统计。分类变量采用Chi2或Fisher精确检验;对于连续变量t检验或Man Whitney检验,考虑p<0.05有统计学意义。结果:共行VCP 290例。在PRP患者(122例)中,18%(23例)为正常,81%(99例)为非特异性。在SRP患者(168例)中,8%为正常,42%为非特异性,51%为SD型(25%为早期,44%为活动性,31%为晚期)。我们发现PRP与SRP患者的RP发展时间(12个月vs 36个月,p<0.01)、VCP正常(18.85% vs 7.4%, p<0.01)、非特异性模式(81.14% vs 41%, p<0.01)有统计学意义。结论:FRS患者以SD型为主,而FRP患者以正常和非特异性型为主。FRS与较长的进化时间有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Capillaroscopic findings and clinical characteristics in patients with primary and secondary Raynaud's phenomenon
Objectives: to describe videocapillaroscopy (VCP) findings in patients with primary Raynaud's phenomenon (PRP) and secondary (SRP); compare demographic and clinical characteristics between both. Materials and methods: observational, analytical, cross-sectional study. Age, occupation, evolution time of RP, connective tissue disease (CTD) and capillaroscopic characteristics were documented. The VCP were reported as normal, nonspecific or early, active, and late SD pattern. Descriptive statistics were performed. Chi2 or Fisher's exact test were used for categorical variables; for continuous variables t test or Man Whitney, considering statistically significant p<0.05. Results: 290 VCP were performed. In patients with PRP (n:122), 18% (n:23) were normal and 81% (n:99) non-specific. In patients with SRP (n:168), 8% were normal, 42% non-specific and 51% with SD pattern (25% early, 44% active, 31% late). We found statistically significant differences: time of evolution of RP in months (12 vs. 36, p<0.01), normal VCP (18.85% vs 7.4%, p<0.01), non-specific pattern (81.14% vs 41%, p<0.01) in patients with PRP vs SRP. Conclusions: in patients with FRS predominated the SD pattern, while in those with FRP the normal and nonspecific pattern was superior. FRS was associated with a longer evolution time.
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