某培训医院男科实验室15年精液分析结果

Gulnaz Kervancioglu, I. Polat, S. Kul, G. Yildirim, I. Alkis, A. Tekirdağ
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摘要

背景:15年来不孕不育门诊转介至男科实验室的不育夫妇男性伴侣精液值的变化和定义。材料和方法:1995年1月至2009年7月,在Bak - rkoy妇幼健康教育研究医院不育科男科实验室对6780名男性患者的9327份精液样本进行了分析。2000年以前的分析是根据1992年世界卫生组织(卫生组织)手册进行的,而2000年以后的分析是根据1999年卫生组织手册进行的。形态学依据Kruger-strict标准进行评价。所有精液分析均由一名具有ART实验室认证的医学博士进行。结果:9327例分析的年分布:1995年293例,2000年492例,2002年715例,2007年1217例,2008年1122例,2009年634例。1995 ~ 1999年,正常精子样品的比例逐渐下降,此后一直保持稳定。注意到,尽管2004年畸形精子数量有所减少,但OAT的比例有所增加,2007年又开始稳步上升,无精子样本的比例继续保持在同一水平。6780例患者中正常精子分布占35%,无精子分布占4%,畸形精子分布占57%。结论:精液分析次数和定期转诊男科实验室精液分析的患者数量逐年增加。对这一增长的解释与社会保障覆盖规则(SGK)的变化有关。正常精子症的减少和稳定水平以及OAT和畸形精子症的增加可能与我们单位越来越多地进行的宫内人工授精和辅助生殖技术(ART)有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
RESULTS OF 15 YEARS SEMEN ANALYSIS IN A TRAINING HOSPITAL ANDROLOGY LABORATORY
SUMMARY Background: Changes and definitions of the semen values of male partners of infertile couples referred by Infertility clinic to the andrology laboratory in 15 years period. Materials and methods: Between January 1995 and July 2009, 9327 semen samples of 6780 male patients were analyzed at Bak›rkoy Maternal and Children's Health Education and Research Hospital, Department of Infertility Andrology laboratory. Analysis made prior to 2000 were according to the World Health Organization (WHO) manualof 1992, while those made after 2000 WHO manual of 1999. Morphology was evaluated according to Kruger-strict criteria. All of semen analysis were performed by one doctor (MD Ph.D.) who has a certification of ART laboratory. Results: Annual distribution of 9327 analyses: 293 in 1995, 492 in 2000, 715 in 2002, 1217 in 2007, 1122 in 2008, 634 in 2009. The percentage of normospermic samples reduced gradually from 1995 to 1999 after that it persisted in a stable line. It was noted that the percentage of oligoastenoteratozoospermic samples (OAT) was increased, despite a reduction in teratozoospermies in 2004, it steadily started to increase again in 2007, and the the percentage of azoospermic sample continued at the same level. Of 6780 patients 35% normospermic, 4% azospermic and 57% teratozoospermic distribution were noticed. Conclusion: The number of semen analysis and the number of patients that were referred to andrology laboratory for semen analyses regularly increased every year. The explanation of this increase was associated with the change of the Social Security coverage rules (SGK). First reduction and than steady levels of normospermia and the increase of OAT and teratozoospermia, could be associated with intrauterine insemination which is increasingly performed in our unit and assisted reproductive techniques (ART).
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