"Evaluating the Role of Central Vein Sign as an Imaging Biomarker for Developing Multiple Sclerosis"

BACKGROUND Multiple sclerosis disease is a chronic disorder starting in youth adulthood [1]. It is a neurodegenerative disturbance that attacks the central nervous system (CNS). It is characterized by the presence of many inflamed lesions caused by demyelination which might result in loss of myelin sheath. These lesions are not specific ABSTRACT Background: Multiple sclerosis (MS) is considered as one of the common chronic disorders. It affects young population which is commonly observed as inflamed lesions and caused by demyelination of the myelin sheath. It might consequently lead to loss of myelin sheath. These lesions are not specific to MS but could mimic several pathological conditions. They are hardly undifferentiated by medical imaging techniques. With the increased number of MS patients, who may have an actual disability. Therefore, the accurate diagnostic imaging of MS lesions has been highly demands. Aims: This paper aims to review the role of magnetic resonance imaging