{"title":"基于软件的高频升压改进膜片钳放大器","authors":"Jie Luo, Zhenhua Song, A. Qu","doi":"10.1109/INEC.2016.7589385","DOIUrl":null,"url":null,"abstract":"The large feedback resistors in the headstage of the patch-clamp amplifier lower the recording bandwidth to less than 100 Hz. A software-based high-frequency boost (SHB) was introduced in this paper. The algorithm consisted of two parts: 1) headstage dynamic characteristic identification using 4SID method; 2) bandwidth compensation using zero-pole matching. Both time and frequency domain analysis demonstrated SHB should be a satisfied alternative to the traditional high-frequency boost circuit.","PeriodicalId":416565,"journal":{"name":"2016 IEEE International Nanoelectronics Conference (INEC)","volume":"309 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2016-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Improved patch-clamp amplifier using software-based high-frequency boost\",\"authors\":\"Jie Luo, Zhenhua Song, A. Qu\",\"doi\":\"10.1109/INEC.2016.7589385\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The large feedback resistors in the headstage of the patch-clamp amplifier lower the recording bandwidth to less than 100 Hz. A software-based high-frequency boost (SHB) was introduced in this paper. The algorithm consisted of two parts: 1) headstage dynamic characteristic identification using 4SID method; 2) bandwidth compensation using zero-pole matching. Both time and frequency domain analysis demonstrated SHB should be a satisfied alternative to the traditional high-frequency boost circuit.\",\"PeriodicalId\":416565,\"journal\":{\"name\":\"2016 IEEE International Nanoelectronics Conference (INEC)\",\"volume\":\"309 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2016-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"2016 IEEE International Nanoelectronics Conference (INEC)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/INEC.2016.7589385\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"2016 IEEE International Nanoelectronics Conference (INEC)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/INEC.2016.7589385","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Improved patch-clamp amplifier using software-based high-frequency boost
The large feedback resistors in the headstage of the patch-clamp amplifier lower the recording bandwidth to less than 100 Hz. A software-based high-frequency boost (SHB) was introduced in this paper. The algorithm consisted of two parts: 1) headstage dynamic characteristic identification using 4SID method; 2) bandwidth compensation using zero-pole matching. Both time and frequency domain analysis demonstrated SHB should be a satisfied alternative to the traditional high-frequency boost circuit.
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