微波辐照多组分反应简单高效合成2,4,5-三芳基取代咪唑衍生物

H. D. Hanoon, S. M. Radhi, S. Abbas
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引用次数: 2

摘要

以苯、芳香醛、乙酸铵和8-羟基-7-碘喹啉-5-磺酸(HISA)为催化剂,在微波照射下,在温和的反应条件下进行四组分缩合反应,合成了一些2,4,5-三芳基取代咪唑衍生物。本方法具有收率高、生态友好、反应时间短、催化剂便宜、易得等优点。以苯、芳香醛、乙酸铵和8-羟基-7-碘喹啉-5-磺酸(HISA)为催化剂,在微波照射下,在温和的反应条件下进行四组分缩合反应,合成了一些2,4,5-三芳基取代咪唑衍生物。本方法具有收率高、生态友好、反应时间短、催化剂便宜、易得等优点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Simple and efficient synthesis of 2,4,5-triarylsubstituted imidazole derivatives via a multicomponent reaction using microwave irradiation
The simple and efficient procedure for a four-component condensation of benzil, aromatic aldehydes, ammonium acetate and 8-hydroxy-7-iodoquinoline-5-sulfonic acid (HISA) as the catalyst under microwave irradiation in mild reaction conditions to synthesis some of 2,4,5-triarylsubstituted imidazole derivatives. The present method is excellent yields, eco-friendly, shorter reaction time, inexpensive and readily available catalyst.The simple and efficient procedure for a four-component condensation of benzil, aromatic aldehydes, ammonium acetate and 8-hydroxy-7-iodoquinoline-5-sulfonic acid (HISA) as the catalyst under microwave irradiation in mild reaction conditions to synthesis some of 2,4,5-triarylsubstituted imidazole derivatives. The present method is excellent yields, eco-friendly, shorter reaction time, inexpensive and readily available catalyst.
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