Effects of Extrusion Temperature and Printing Direction in Bioprinting on Profile Accuracy of 3D Printed Constructs

In extrusion-based bioprinting, 3D printing process parameters affect dimensional accuracy of printed constructs. However, little information is currently available on effects of extrusion temperature and printing direction on dimensional accuracy of 3D printed constructs using Alginate:Methylcelluolose hydrogel. In this study, strand thickness of 3D printed constructs printed at temperature of 35°C, 40°C, 45°C and at vertical and horizontal printing direction were measured. The statistical analysis revealed that extrusion temperature and printing direction have significant effect on the strand thickness of 3D printed constructs.