{"title":"阿富汗喀布尔Amiri医院心胸血管外科法洛四联症患者全矫正后的早期结果(单中心研究)","authors":"M Timorian, R. Rahman, Saboor As","doi":"10.16966/2469-6714.146","DOIUrl":null,"url":null,"abstract":"Tetralogy of Fallot is the most common cyanotic congenital heart disease. The first complete repair of tetralogy of Fallot was successfully performed by C. Walton Lillehi and his team in 1954, but first total correction performed at department of cardiothoracic and vascular surgery Amiri Medical Complex Kabul Afghanistan in 2015, despite some advocates of routine two-stage repair in infancy, during the early 1990s reports documented improve early results with primary repair was associated with improved outcome compared to a two-stage approach. The purpose of this study was to analyze the early postoperative result in total correction for the first time in Afghanistan. Method: The purpose of this study was to evaluate the early outcome after total correction in 180 consecutive patients with a mean age of 5-30 years who underwent total correction surgery in a single center Amiri Medical Complex, Kabul, Afghanistan between August 2015 and October 2018. 8 patients had initial palliative operations (modified BT shunt) in outside centers and referred to us for total correction. The trans annular pericardial patch was inserted in 133(73.8%) patients. 32(17.7%) patients repaired by trans atrial total correction (ventricular septal defect, right ventricular outflow tract muscle band resection and pulmonary valvotomy done through the right atrium ) for 5(2.7%) patients with absent pulmonary valve, monocuspid and bicuspid pulmonary valve reconstructed with a pericardial patch. Result: Mean follow up was (1-3) months postoperatively, the mortality rate was (8.8%). Most of the patients who repaired with trans annular patch had free pulmonary valve regurgitation post-operative period by transthoracic echocardiography 26 patients had the excellent function of their native repaired pulmonary valve and monocusp, bicuspid reconstructed pulmonary valve. The peak gradient of right ventricular outflow tract was between 10 to 35 mmHg postoperatively. 22 patients had small (tiny) residual ventricular septal defect and none of the patients had complete heart block (0%). Conclusion: Total correction for tetralogy of Fallot patients may have low operative mortality and provide excellent short and long term survival in modern centers; this experience suggests that total correction for tetralogy of Fallot patients would have good short term outcomes in developed countries.","PeriodicalId":112163,"journal":{"name":"Clinical Research: Open Access","volume":"51 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Early Outcomes after Total Correction for Tetralogy of Fallot Patients at Department of Cardiothoracic and Vascular Surgery Amiri Medical Complex Kabul-Afghanistan (A Single Center Study)\",\"authors\":\"M Timorian, R. Rahman, Saboor As\",\"doi\":\"10.16966/2469-6714.146\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Tetralogy of Fallot is the most common cyanotic congenital heart disease. The first complete repair of tetralogy of Fallot was successfully performed by C. Walton Lillehi and his team in 1954, but first total correction performed at department of cardiothoracic and vascular surgery Amiri Medical Complex Kabul Afghanistan in 2015, despite some advocates of routine two-stage repair in infancy, during the early 1990s reports documented improve early results with primary repair was associated with improved outcome compared to a two-stage approach. The purpose of this study was to analyze the early postoperative result in total correction for the first time in Afghanistan. Method: The purpose of this study was to evaluate the early outcome after total correction in 180 consecutive patients with a mean age of 5-30 years who underwent total correction surgery in a single center Amiri Medical Complex, Kabul, Afghanistan between August 2015 and October 2018. 8 patients had initial palliative operations (modified BT shunt) in outside centers and referred to us for total correction. The trans annular pericardial patch was inserted in 133(73.8%) patients. 32(17.7%) patients repaired by trans atrial total correction (ventricular septal defect, right ventricular outflow tract muscle band resection and pulmonary valvotomy done through the right atrium ) for 5(2.7%) patients with absent pulmonary valve, monocuspid and bicuspid pulmonary valve reconstructed with a pericardial patch. Result: Mean follow up was (1-3) months postoperatively, the mortality rate was (8.8%). Most of the patients who repaired with trans annular patch had free pulmonary valve regurgitation post-operative period by transthoracic echocardiography 26 patients had the excellent function of their native repaired pulmonary valve and monocusp, bicuspid reconstructed pulmonary valve. The peak gradient of right ventricular outflow tract was between 10 to 35 mmHg postoperatively. 22 patients had small (tiny) residual ventricular septal defect and none of the patients had complete heart block (0%). Conclusion: Total correction for tetralogy of Fallot patients may have low operative mortality and provide excellent short and long term survival in modern centers; this experience suggests that total correction for tetralogy of Fallot patients would have good short term outcomes in developed countries.\",\"PeriodicalId\":112163,\"journal\":{\"name\":\"Clinical Research: Open Access\",\"volume\":\"51 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Research: Open Access\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.16966/2469-6714.146\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Research: Open Access","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.16966/2469-6714.146","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
法洛四联症是最常见的青紫型先天性心脏病。1954年,C. Walton Lillehi和他的团队成功完成了法洛四联症的第一次完全修复,但2015年在阿富汗喀布尔的阿米里医疗中心(Amiri Medical Complex)的心肺血管外科进行了第一次完全修复,尽管一些人主张在婴儿期进行常规的两阶段修复,但在20世纪90年代初的报告中,与两阶段方法相比,初级修复的早期结果有所改善。本研究的目的是分析阿富汗首次全矫正术后早期的结果。方法:本研究的目的是评估2015年8月至2018年10月在阿富汗喀布尔Amiri医疗中心接受全矫正手术的180例平均年龄为5-30岁的连续患者的全矫正术后早期结果。8例患者在外部中心进行了最初的姑息性手术(改良BT分流),并转介到我们进行全面矫正。133例(73.8%)患者置入经环心包贴片。32例(17.7%)经心房全矫正(室间隔缺损、右心室流出道肌束切除及经右心房肺动脉瓣切开术),5例(2.7%)肺动脉瓣缺失患者经心包补片重建单尖瓣和双尖瓣。结果:术后平均随访(1 ~ 3)个月,死亡率(8.8%)。经胸超声心动图显示,经环形补片修复的患者术后大部分出现游离肺动脉瓣返流,26例患者原发修复的肺动脉瓣及单尖、双尖重建的肺动脉瓣功能良好。术后右心室流出道梯度峰值在10 ~ 35 mmHg之间。22例存在小(微小)残余室间隔缺损,无完全性心脏传导阻滞(0%)。结论:现代中心对法洛四联症患者进行全面矫正手术死亡率低,短期和长期生存率高;这一经验表明,在发达国家,对法洛四联症患者进行全面矫正具有良好的短期效果。
Early Outcomes after Total Correction for Tetralogy of Fallot Patients at Department of Cardiothoracic and Vascular Surgery Amiri Medical Complex Kabul-Afghanistan (A Single Center Study)
Tetralogy of Fallot is the most common cyanotic congenital heart disease. The first complete repair of tetralogy of Fallot was successfully performed by C. Walton Lillehi and his team in 1954, but first total correction performed at department of cardiothoracic and vascular surgery Amiri Medical Complex Kabul Afghanistan in 2015, despite some advocates of routine two-stage repair in infancy, during the early 1990s reports documented improve early results with primary repair was associated with improved outcome compared to a two-stage approach. The purpose of this study was to analyze the early postoperative result in total correction for the first time in Afghanistan. Method: The purpose of this study was to evaluate the early outcome after total correction in 180 consecutive patients with a mean age of 5-30 years who underwent total correction surgery in a single center Amiri Medical Complex, Kabul, Afghanistan between August 2015 and October 2018. 8 patients had initial palliative operations (modified BT shunt) in outside centers and referred to us for total correction. The trans annular pericardial patch was inserted in 133(73.8%) patients. 32(17.7%) patients repaired by trans atrial total correction (ventricular septal defect, right ventricular outflow tract muscle band resection and pulmonary valvotomy done through the right atrium ) for 5(2.7%) patients with absent pulmonary valve, monocuspid and bicuspid pulmonary valve reconstructed with a pericardial patch. Result: Mean follow up was (1-3) months postoperatively, the mortality rate was (8.8%). Most of the patients who repaired with trans annular patch had free pulmonary valve regurgitation post-operative period by transthoracic echocardiography 26 patients had the excellent function of their native repaired pulmonary valve and monocusp, bicuspid reconstructed pulmonary valve. The peak gradient of right ventricular outflow tract was between 10 to 35 mmHg postoperatively. 22 patients had small (tiny) residual ventricular septal defect and none of the patients had complete heart block (0%). Conclusion: Total correction for tetralogy of Fallot patients may have low operative mortality and provide excellent short and long term survival in modern centers; this experience suggests that total correction for tetralogy of Fallot patients would have good short term outcomes in developed countries.