Exploration of animal models to assess Shrama (Fatigue) with reference to Weight Loaded Forced Swimming Test

The World Health Organization 2003 has estimated that 80 of the population of developing countries depend on traditional medicines to sustain their primary health care needs. India is one of the most medico-culturally diverse countries in the world where the medicinal plant sector is part of a time honoured tradition that is respected even today. Here the main traditional systems of medicine include Ayurveda Unani and Siddha. In Ayurveda many herbs herbal preparations are mentioned to combat Fatigue and acts as a tonic. Fatigue the seventh most common symptom in primary health care is one of the least understood conditions in medical science. Chronic fatigue is an illness characterized by profound disabling fatigue accompanied by numerous neurological and psychosomatic complaints. In this illness various neuroendocrine abnormalities contribute to the impaired energy and mood. In pharmacology many models are established to assess the fatigue in which Weight Loaded Forced Swimming Test can be used to Assess Shrama.