连续顺磁电泳血细胞微分离器

TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664) Pub Date : 2003-08-04 DOI:10.1109/SENSOR.2003.1216994

Ki-Ho Han, J. Landers, A. B. Frazier

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引用次数: 6

摘要

采用高梯度磁分离(HGMS)方法，研制了一种连续顺磁电泳(PMP)微分离器，用于从全血中直接分离血细胞。针对高磁性分离力，采用微加工技术制备PMP分离器，利用其磁性直接从全血中分离红血球和白细胞。推导了PMP微分离器的理论模型，并将仿真值与计算值进行了比较。用血细胞计定量分析表明，目前的PMP微分离器从全血中分离出92%的红细胞。

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Continuous paramagnetophoretic microseparator for blood cells

This paper presents a continuous paramagnetophoretic (PMP) microseparator for directly separating blood cells from whole blood by using a high gradient magnetic separation (HGMS) method. For high magnetic separation force, the present PMP separator is fabricated by microfabrication technology, and directly separates red and white blood cells from whole blood based on their magnetic properties. The theoretical model of the PMP microseparator is derived, and simulated values are compared with calculated values. A quantitative analysis using a hemocytometer shows that 92% of red blood cells are separated from whole blood by the present PMP microseparator.

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TRANSDUCERS '03. 12th International Conference on Solid-State Sensors, Actuators and Microsystems. Digest of Technical Papers (Cat. No.03TH8664)

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