暴力犯罪精神障碍患者的临床、社会特征及生化指标特征

O. Makushkina, V. Golenkova
{"title":"暴力犯罪精神障碍患者的临床、社会特征及生化指标特征","authors":"O. Makushkina, V. Golenkova","doi":"10.47026/2413-4864-2022-4-37-46","DOIUrl":null,"url":null,"abstract":"The relevance of the study is conditioned by the need to develop effective methods to prevent public danger arising from persons suffering from mental disorders, with identification of factors that influence aggressive behavior formation in order to improve measures to prevent crimes related to violence. the purpose of this work was to study the socio-demographic, clinical and psychopathological features and biochemical parameters in persons with mental disorders who committed violent crimes. the scientific novelty is determined by the importance of establishing the features of the complex influence of clinical, biological and social factors on the tendency to heteroaggression, the lack of scientifically substantiated data on the role of neurotransmitter and hormonal systems in aggressive behavior formation in patients with severe forms of mental pathology. Materials and methods. the research sample consisted of 100 respondents aged 18 to 60 years with a verified diagnosis of a severe mental disorder and the fact of criminal prosecution for violent crimes. the clinical features of the patients were evaluated using a clinical-psychopathological method with identification of the leading characteristics in psychopathological symptoms and syndromes. Standardized assessment of clinical characteristics was provided by the use of the psychometric methodology \"Positive and Negative Syndrome Scale\" (PANSS), the methodology \"Structured Assessment of Unsafe Behavior Risk\" (SOROP). for laboratory testing, blood and urine samples were used to determine the levels of serotonin, dopamine, cortisol, testosterone, free T3 (free T3), estradiol. Results. the most common clinical and social characteristics of persons with severe mental disorders and persistent aggressive criminal behavior were identified and described. in the majority of respondents, the indicators of the neurotransmitter system (serotonin, dopamine levels) were found to differ significantly from the reference values. a negative correlation was determined between serotonin excretion and the sum of points according to SOROP technique, as well as the subscale of aggression, which is part of the indicators in PANSS technique. Conclusions. the obtained data contribute to understanding the nature of heteroaggression in persons with mental disorders, indicating the need for further studying the relationship of social, clinical and biological parameters, determining their role in aggressive behavior formation in this contingent of patients.","PeriodicalId":249759,"journal":{"name":"Acta medica Eurasica","volume":"125 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"CLINICAL AND SOCIAL CHARACTERISTICS AND FEATURES OF BIOCHEMICAL INDICATORS IN PERSONS WITH MENTAL DISORDERS WHO HAVE COMMITTED VIOLENT CRIMES\",\"authors\":\"O. Makushkina, V. Golenkova\",\"doi\":\"10.47026/2413-4864-2022-4-37-46\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The relevance of the study is conditioned by the need to develop effective methods to prevent public danger arising from persons suffering from mental disorders, with identification of factors that influence aggressive behavior formation in order to improve measures to prevent crimes related to violence. the purpose of this work was to study the socio-demographic, clinical and psychopathological features and biochemical parameters in persons with mental disorders who committed violent crimes. the scientific novelty is determined by the importance of establishing the features of the complex influence of clinical, biological and social factors on the tendency to heteroaggression, the lack of scientifically substantiated data on the role of neurotransmitter and hormonal systems in aggressive behavior formation in patients with severe forms of mental pathology. Materials and methods. the research sample consisted of 100 respondents aged 18 to 60 years with a verified diagnosis of a severe mental disorder and the fact of criminal prosecution for violent crimes. the clinical features of the patients were evaluated using a clinical-psychopathological method with identification of the leading characteristics in psychopathological symptoms and syndromes. Standardized assessment of clinical characteristics was provided by the use of the psychometric methodology \\\"Positive and Negative Syndrome Scale\\\" (PANSS), the methodology \\\"Structured Assessment of Unsafe Behavior Risk\\\" (SOROP). for laboratory testing, blood and urine samples were used to determine the levels of serotonin, dopamine, cortisol, testosterone, free T3 (free T3), estradiol. Results. the most common clinical and social characteristics of persons with severe mental disorders and persistent aggressive criminal behavior were identified and described. in the majority of respondents, the indicators of the neurotransmitter system (serotonin, dopamine levels) were found to differ significantly from the reference values. a negative correlation was determined between serotonin excretion and the sum of points according to SOROP technique, as well as the subscale of aggression, which is part of the indicators in PANSS technique. Conclusions. the obtained data contribute to understanding the nature of heteroaggression in persons with mental disorders, indicating the need for further studying the relationship of social, clinical and biological parameters, determining their role in aggressive behavior formation in this contingent of patients.\",\"PeriodicalId\":249759,\"journal\":{\"name\":\"Acta medica Eurasica\",\"volume\":\"125 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-12-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta medica Eurasica\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47026/2413-4864-2022-4-37-46\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta medica Eurasica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47026/2413-4864-2022-4-37-46","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

这项研究的意义在于,需要制定有效的方法,防止精神失常患者造成公共危险,并确定影响形成攻击性行为的因素,以改进预防与暴力有关的犯罪的措施。本研究的目的是研究暴力犯罪精神障碍患者的社会人口学、临床和精神病理特征及生化指标。确立临床、生物和社会因素对异向攻击倾向的复杂影响特征的重要性,以及神经递质和激素系统在严重精神病理患者攻击行为形成中的作用缺乏科学证实的数据,决定了科学的新颖性。材料和方法。研究样本包括100名年龄在18岁至60岁之间的受访者,他们被确诊患有严重精神障碍,并曾因暴力犯罪受到刑事起诉。使用临床-精神病理学方法评估患者的临床特征,并确定精神病理学症状和综合征的主要特征。临床特征的标准化评估采用心理测量方法“正负综合征量表”(PANSS)和“不安全行为风险结构化评估”(SOROP)。在实验室测试中,血液和尿液样本被用来测定血清素、多巴胺、皮质醇、睾酮、游离T3(游离T3)、雌二醇的水平。结果。鉴定并描述了具有严重精神障碍和持续攻击性犯罪行为的人最常见的临床和社会特征。在大多数受访者中,神经递质系统的指标(血清素,多巴胺水平)被发现与参考值有显著差异。血清素排泄量与SOROP积分和PANSS攻击分量表呈负相关。结论。这些数据有助于理解精神障碍患者的异性攻击本质,表明需要进一步研究社会、临床和生物学参数的关系,确定它们在这类患者攻击行为形成中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
CLINICAL AND SOCIAL CHARACTERISTICS AND FEATURES OF BIOCHEMICAL INDICATORS IN PERSONS WITH MENTAL DISORDERS WHO HAVE COMMITTED VIOLENT CRIMES
The relevance of the study is conditioned by the need to develop effective methods to prevent public danger arising from persons suffering from mental disorders, with identification of factors that influence aggressive behavior formation in order to improve measures to prevent crimes related to violence. the purpose of this work was to study the socio-demographic, clinical and psychopathological features and biochemical parameters in persons with mental disorders who committed violent crimes. the scientific novelty is determined by the importance of establishing the features of the complex influence of clinical, biological and social factors on the tendency to heteroaggression, the lack of scientifically substantiated data on the role of neurotransmitter and hormonal systems in aggressive behavior formation in patients with severe forms of mental pathology. Materials and methods. the research sample consisted of 100 respondents aged 18 to 60 years with a verified diagnosis of a severe mental disorder and the fact of criminal prosecution for violent crimes. the clinical features of the patients were evaluated using a clinical-psychopathological method with identification of the leading characteristics in psychopathological symptoms and syndromes. Standardized assessment of clinical characteristics was provided by the use of the psychometric methodology "Positive and Negative Syndrome Scale" (PANSS), the methodology "Structured Assessment of Unsafe Behavior Risk" (SOROP). for laboratory testing, blood and urine samples were used to determine the levels of serotonin, dopamine, cortisol, testosterone, free T3 (free T3), estradiol. Results. the most common clinical and social characteristics of persons with severe mental disorders and persistent aggressive criminal behavior were identified and described. in the majority of respondents, the indicators of the neurotransmitter system (serotonin, dopamine levels) were found to differ significantly from the reference values. a negative correlation was determined between serotonin excretion and the sum of points according to SOROP technique, as well as the subscale of aggression, which is part of the indicators in PANSS technique. Conclusions. the obtained data contribute to understanding the nature of heteroaggression in persons with mental disorders, indicating the need for further studying the relationship of social, clinical and biological parameters, determining their role in aggressive behavior formation in this contingent of patients.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信